Hormonal fluctuations and an imbalance of estrogen and testosterone levels have proven to be a direct cause of acne. For this reason, many experience an onslaught of breakouts during puberty and pregnancy. The brain releases a GnRH hormone when an adolescent begins puberty, which in turn signals the pituitary gland to release two additional androgens. Androgens make the sebaceous glands produce more sebum, causing it to occupy too much space within the pore and preventing the full expulsion of dead skin cells and debris. Fluctuations in hormones also cause many women to experience acne during pregnancy and a worsening of breakouts during menstrual cycles.
Pimples are raised red spots with a white center that develop when blocked hair follicles become inflamed or infected with bacteria. Blockages and inflammation that develop deep inside hair follicles produce cystlike lumps beneath the surface of your skin. Other pores in your skin, which are the openings of the sweat glands, aren't usually involved in acne.